DrugInfoSys

Guaifenesin

Also known as: Glyceryl Guaiacolate

Drug #1281

Guaifenesin is expectorant. Chemically Guaifenesin is 3-(o-methoxyphenoxy)-1, 2-propanediol. It reduces the viscosity of phlegm and mucous in the lungs. It enables coughing up of mucous.

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Primary Characteristics

Guaifenesin is also known as Glyceryl Guaiacolate.

It is of Synthetic origin and belongs to Propanediol.

Molecular Weight: 198.22 · Solubility in Water: 1 in 60 - 70 · Solubility in Alcohol: soluble · Non-proprietary name: Guaifenesin.

Molecular structure of Guaifenesin

Pharmacokinetics

Elimination: plasma half-life is 1 hr, renal excretion is urine.

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Indications

Guaifenesin is primarily indicated in conditions like Productive cough.

Contraindications

Guaifenesin is contraindicated in conditions like Hypersensitivity reactions.

Dosage

Guaifenesin's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
300 mg300 mgEvery 4hPO
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Moderate1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Guaifenesin is known to cause more or less tolerable side effects which are usually transient. These include Dizziness, Drowsiness, Headache, Nausea and vomiting, Rashes , Stomach pain, Stomach upset.

Warnings / Precautions

Guaifenesin should not use in excessive amount because may cause nausea and vomiting. If cough persists for more than one week, accompanied by high fever, rash or headache, consult the physician. Use caution when driving, operating machinery, or performing other hazardous activities. Guaifenesin may cause dizziness. If you experience dizziness, avoid these activities.

Available Brands

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Single Ingredient

Syrup
50 mg/5ml

Multi-Ingredient Combinations

Syrup
100 mg/5ml90 mg/5ml
Syrup
30 mg/5ml50 mg/5ml50 mg/ml66.5 mg/5ml
Tabs
600 mg

Storage Conditions

Guaifenesin should be stored Syrup. Tab.

Drug Classification

  1. 1.25.2.2 — Expectorants

Manufacturers