Diphenyl Pyraline

Drug #1238

Diphenyl Pyraline (HCl) is a H1 receptor antagonist with anticholinergic and seddative effects. Diphenyl Pyraline (HCl) is used as antihistaminic agent in the treatment of allergic symptoms. Diphenyl Pyraline (HCl) is administered orally.

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Primary Characteristics

Diphenyl Pyraline is also known as Diphenyl Pyraline (HCl).

It is of Synthetic origin and belongs to Aminio alkyle ether.

Molecular Weight: 317.9 · Solubility in Water: 1 in 1 · Solubility in Alcohol: 1 in 3 · Non-proprietary name: Diphenyl Pyraline.

Molecular structure of Diphenyl Pyraline

Pharmacokinetics

Absorption: Diphenyl Pyraline has an oral bioavailability is 141.5% (±139.5%).

Elimination: it is metabolised via Liver.

Indications

Diphenyl Pyraline is primarily indicated in conditions like Cold, Cough, Pruritus, Rhinitis, Skin diseases.

Diphenyl Pyraline is also indicated for secondary conditions like Parkinsonism.

Contraindications

Diphenyl Pyraline is contraindicated in conditions like Heart disease, Jaundice, Urinary tract infection, Glaucoma.

Dosage

Diphenyl Pyraline's dosage details are as follows:

Dose	Single Dose	Frequency	Instructions
Adult Dosage
6 mg/day	6 mg/day	—	3-4 divided doses.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown2 interactions

3 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Diphenyl Pyraline in overdosage may give rise to further complications which include Anemia , Anemia , Hypotension , Hypotension , Paresthesia, Anemia, Anemia.

Diphenyl Pyraline produces potentially life-threatening effects which include Convulsions . Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Diphenyl Pyraline are Extrapyramidal effects , CNS effects.

Diphenyl Pyraline is known to cause more or less tolerable side effects which are usually transient. These include Confusion, Diplopia, Drowsiness, Insomnia, Myalgia, Rashes , Sedation , Sensitivity , SweatingX.

Warnings / Precautions

Diphenyl pyraline should be used with caution in bone marrow depression. Patients should observe caution while driving or performing other task requiring alertness because it may cause drowsiness. It should be used with caution in patients with urinary retention, history of bronchial asthma, hyperthyroidism, cardiovascular or liver disease. It should be used with caution in person with acute or chronic respiratory impairment, especially in children. Do not administer S/C because irritation or lesion may occur.

Available Brands

None recorded.

Storage Conditions

Diphenyl Pyraline should be stored .

Drug Classification

1.3 — Anti-allergics (Antihistamines) and drugs used in anaphylaxis
2.25.2.1 — Cold preparations