Oxtriphylline (Choline Theophyllinate)

Drug #1228

Oxtriphylline (Choline Theophyllinate) is a choline salt of theophylline. It contains 64% theophylline by weight. Oxtriphylline (Choline Theophyllinate) is more soluble and more stable, better absorbed from gastro-intestinal, causes less gastric irritation. Hence, Oxtriphylline (Choline Theophyllinate) is effective orally in the management of acute bronchial asthma and for reversible bronchospasm. Development of tolerance is infrequent; therefore Oxtriphylline (Choline Theophyllinate) is useful for long-term therapy.

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Primary Characteristics

It is of Synthetic origin.

Molecular Weight: 283.33 · Solubility in Water: 1 in 1 · Solubility in Alcohol: freely · Non-proprietary name: Oxtriphylline (Choline Theophyllinate) · pH: 10.3.

Molecular structure of Oxtriphylline (Choline Theophyllinate)

Pharmacokinetics

None recorded.

Indications

Oxtriphylline (Choline Theophyllinate) is primarily indicated in conditions like Asthma, Bronchitis, Bronchospasm, Emphysema.

Contraindications

Oxtriphylline (Choline Theophyllinate) is contraindicated in conditions like Peptic ulcer, Gastritis, Hypersensitivity to the drug.

Dosage

Oxtriphylline (Choline Theophyllinate)'s dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
800 mg/day	800 mg/day	—	PO	Should be taken in 4 divided doses.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown9 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Oxtriphylline (Choline Theophyllinate) in overdosage may give rise to further complications which include Palpitation , Tremors , CNS stimulation.

The signs and symptoms that are produced after acute overdosage of Oxtriphylline (Choline Theophyllinate) are Hypotension, Vomiting, Tachycardia , Convulsions , Dehydration, Diuresis, Metabolic acidosis, Electrolyte disturbances, Agitation.

Oxtriphylline (Choline Theophyllinate) is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Anxiety, Bleeding , Diarrhea, Dizziness, Headache, Insomnia, Nausea and vomiting, Restlessness.

Warnings / Precautions

Oxtriphylline should be used with caution in patients with severe cardiac, kidney or liver disease, hyperthyroidism, congestive heart failure (CHF), peptic ulcer. It should be used with caution in neonates & elderly persons.

Available Brands

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Multi-Ingredient Combinations

Syrup

100 mg/5ml

Storage Conditions

Oxtriphylline (Choline Theophyllinate) should be stored Syrup. Tab.

Drug Classification

1.25.1.2 — Inhalants

Manufacturers

Manufacturers of Oxtriphylline (Choline Theophyllinate) in Pakistan:

Dr.Raza