Bifonazole
Bifonazole is imidazole antifungal with a broad spectrum of activity.Bifonazole is used topically in the treatment of fungal infections of skin and nail.
Primary Characteristics
It is of Synthetic origin and belongs to Imidazole.
It is classified in Antifungals pharmacological group.
Molecular Weight: 310.4 · Solubility in Water: 2.46-3mg/mL · Solubility in Alcohol: null · Non-proprietary name: Bifonazole.
Pharmacokinetics
Absorption: Bifonazole has an oral bioavailability is 1.55% (±0.95%).
Elimination: it is metabolised via hepatic, plasma half-life is 1-2hrs.
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Indications
Bifonazole is primarily indicated in conditions like Mycoses, Skin fungal infection, Superficial infections.
Contraindications
Bifonazole is contraindicated in conditions like Hypersensitivity to any component of product.
Dosage
Bifonazole's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1 % | 1 % | Every 24h | Topical | For 2 weeks after cure. |
| Paediatric Dosage (20kg) | ||||
| 1 % | 1 % | Every 24h | Topical | For 2 weeks after cure. |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Bifonazole is known to cause more or less tolerable side effects which are usually transient. These include Burning, Itching.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.13.1 — Antifungals, topical