DrugInfoSys

Influenza Vaccine

Drug #1184

Influenza Vaccine is a sterile aqueous suspension of suitable strain or strains of influenza virus types A and B, either individually or mixed, grown individually in embryonated hen eggs and inactivated so that they retain their antigenic properties. The composition of vaccine is changed every year in respose to antigenic shifts and changes in prevalence of influenza virus strain. The vaccine is usually bivalent or trivalent, containing one or two influenza virus A strains and one influenza virus B strain. Annual immunization before November is recommended for high risk individuals (persons over 65 years of age and persons with chronic disease). Influenza Vaccine is used for active immunization against influenza, Influenza Vaccine is indicated only for immunization against those strains of viruses from which the vaccine is prepared or against closely related strains.

Primary Characteristics

It is of Semi Synthetic origin.

It is classified in Vaccines pharmacological group.

Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Influenza Vaccine.

Molecular structure of Influenza Vaccine

Pharmacokinetics

None recorded.

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Indications

Influenza Vaccine is primarily indicated in conditions like Influenza prophylaxis.

Contraindications

Influenza Vaccine is contraindicated in conditions like Thrombocytopenia, Febrile illness, Hypersensitivity.

Dosage

Influenza Vaccine's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
0.5 ml0.5 mlIM Once,Same for different age group
Paediatric Dosage (20kg)
0.5 ml0.5 ml6 months - 3 years the 2nd dose should be given 4 weeks after the first dose.
0.5 ml0.5 mlIV/IMSingle Dose, Recomm. for 5-12 Years of Children
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown5 interactions
Major1 interaction
Moderate1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Influenza Vaccine in overdosage may give rise to further complications which include Convulsions , Thrombocytopenia , Angioedema , Angioedema , Neuralgia , Neuritis, Encephalomyelitis, Guillian-Barre syndrome.

Influenza Vaccine is known to cause more or less tolerable side effects which are usually transient. These include Allergic reactions, Anaphylactic shock, Fever, Flue like syndrome, Malaise, Pain , Paresthesias, Redness, Swelling , Tenderness , Urticaria.

Warnings / Precautions

Influenza vaccine should be used only if clearly needed during pregnancy or lactation. It should be used with caution in patients with any illness, infection or if have any allergy especially to eggs or egg products. The administration of the vaccine should be postponded in subjects suffering from acute febrile illness. The Vaccine only prevent the disease caused by influenza virus, infection with other agents causing flu-like symptoms are not prevented by influenza vaccine. Appropriate medical treatment and supervision should always be readily available in case of a rare anaphylactic reactions following the administration of the vaccine.

Interference in Pathology

Influenza Vaccine may interfere in the diagnosis of False +ve result in serology tests using ELISA method to detect antibodies against HIV, hepatitis C..

Available Brands

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Single Ingredient

Storage Conditions

Influenza Vaccine should be stored Inj.

Drug Classification

  1. 1.19.3.2Vaccines for specific groups of individuals

Manufacturers

Manufacturers of Influenza Vaccine in Pakistan: