DrugInfoSys

Latanoprost

Drug #1172

Latanoprost is a prostaglandin analogue which increases fluid outflow increase from the anterior chamber of the eye and thus reducing intra-ocular pressure (IOP). Used as eye drops in the treatment of glaucoma. May cause eye discomfort, reddening and blurred vision. the eye pressure. Latanoprost is used to treat glaucoma and other problems related to high pressure in the eye.

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Primary Characteristics

It is of Synthetic origin and belongs to Heptenoate.

It is classified in Antiglaucoma pharmacological group. It is also classified under Opthalmic Products .

Molecular Weight: 432.6 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Latanoprost.

Molecular structure of Latanoprost

Pharmacokinetics

Elimination: it is metabolised via Hepatic, plasma half-life is 17 min, renal excretion is extensive.

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Indications

Latanoprost is primarily indicated in conditions like Raised intracranial pressure, Sodium depletion.

Contraindications

Latanoprost is contraindicated in conditions like Hypersensitivity to the drug.

Dosage

Latanoprost's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
0.005 %0.005 %Every 24hOphthalmic
Paediatric Dosage (20kg)
0 – 0——Not recommended for this age group
Neonatal Dosage (3kg)
0 – 0——Not recommended in this age group

Drug Interactions

None recorded.

Side Effects

Latanoprost is known to cause more or less tolerable side effects which are usually transient. These include Angina, athralgia, Backache , Chest pain, dizziness, Dryness of eye, Headache, Lacrimation, Ocular irritation, Oedema, Photophobia , Rashes , Uveitis.

Warnings / Precautions

Latanoprost should be used with caution in patients with kidney or liver disease or any allergy. It can slowly (in years) change the colour of the iris (become browned, If only one eye is being treated, only one eye might darken), the consequences of this are unknown. Consult eye doctor. If develops an eye infection, trauma or have eye surgery, consult with doctor about the continued use of the same dropper bottle. It should be used only when clearly needed during pregnancy. Should be used with cuation in pateints with intraocular inflammention.

Available Brands

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Single Ingredient

Drops
0.01 %0.05 %0.05 mg50 mcg
Eye Drops
50 mcg50 mcg/ml

Multi-Ingredient Combinations

Eye Drops
0.005 %w/v50 mcg/ml

Storage Conditions

Latanoprost should be stored Eye Drops.

Drug Classification

  1. 1.21.4.5 — Prostaglandin analogues

Manufacturers