Hydroquinone

Drug #1149

Hydroquinone is a hypopigmenting agent. Hydroquinone is the reduced form of quinone, containing two hydroxyl groups. Hydroquinone is applied topically to bleach hyperpigmented skin. Hydroquinone is used to temporarily fade dark skin spots such as freckles, lentigo, melasma and age spots.

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Primary Characteristics

It belongs to Quinol.

It is also classified under Dermatological Products .

Molecular Weight: 110.1 · Solubility in Water: 1 in 17 · Solubility in Alcohol: 1 in 4 · Non-proprietary name: Hydroquinone.

Pharmacokinetics

None recorded.

Indications

Hydroquinone is primarily indicated in conditions like Freckles, Hyperpigmentation, Melasma.

Contraindications

Hydroquinone is contraindicated in conditions like Broken skin.

Dosage

Hydroquinone's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
3 %	3 %	Every 12h	Topical	APPLY 2-3 times or as prescribed by the physician.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Moderate1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Hydroquinone in overdosage may give rise to further complications which include Convulsions , Tremors .

The signs and symptoms that are produced after acute overdosage of Hydroquinone are Hives, difficulty in breathing.

Hydroquinone is known to cause more or less tolerable side effects which are usually transient. These include Burning, Itching, Redness, Stinging.

Warnings / Precautions

Hydroquinone should be used only if clearly needed during pregnancy. It should be used with caution in patients with any pre-existing illness, infection or allergy, especially to sulfites.It shoud not be appleid to surnburnt skin, It should not be used to bleach eyelashes or eye brous, constact with eyes should be avoided.

Interference in Pathology

Hydroquinone may interfere in the diagnosis of Plasma Cortisol Test , ACTH Stimulation test, Urinary free cortisol test, ACTH stimulation test.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Cream

2 %2 % w/w 2 %w/w 4 % w/w 4 %w/w 6 %w/w

Gel

2 %w/w 4 %w/w

Lotion

3 %w/w

Multi-Ingredient Combinations

Cream

2 %w/w

Cream

4 %w/w 4 g

Lotion

4 %w/v

Storage Conditions

Hydroquinone should be stored Soln, Cream , Gel.

Drug Classification

1.13.7 — Ultravoilet blocking agents

Manufacturers

Manufacturers of Hydroquinone in Pakistan: