Trimetazidine (Di HCl)
Trimetazidine (Di HCl) is used in angina and in ischaemia of neuro-sensorial tissues.
Primary Characteristics
It belongs to Piperazine.
It is also classified under Antianginal Agents .
Molecular Weight: 339.3 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Trimetazidine (Di HCl).
Pharmacokinetics
Distribution: Trimetazidine (Di HCl) has a volume of distribution is 4.8 l/kg. plasma protein binding is 16 %.
Advertisement
Indications
Trimetazidine (Di HCl) is primarily indicated in conditions like Prevention of hypokalaemia, Prophylaxis of angina.
Contraindications
None recorded.
Dosage
Trimetazidine (Di HCl)'s dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 20 mg | 20 mg | Every 8h | PO | |
| Paediatric Dosage (20kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
| Neonatal Dosage (3kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
Drug Interactions
None recorded.
Side Effects
Trimetazidine (Di HCl) is known to cause more or less tolerable side effects which are usually transient. These include GI upset.
Available Brands
Storage Conditions
Drug Classification
- 1.12.1 — Antianginal drugs