DrugInfoSys

Thiethylperazine

Drug #1061

Thiethylperazine is a phenothiazine similar to chlopromazine, Thiethylperazine is antiemetic, used to treat nausea, vomiting and to manage vertigo.

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Primary Characteristics

It is of Synthetic origin and belongs to Phenothiazine.

It is also classified under Antiemetic/Antivertigo Agents .

Molecular Weight: 399.6 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Thiethylperazine · pH: 3.3.

Molecular structure of Thiethylperazine

Pharmacokinetics

Distribution: Thiethylperazine has a volume of distribution is 2.7 l/kg.

Elimination: renal excretion is 3 %.

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Indications

Thiethylperazine is primarily indicated in conditions like Acne, Brain trauma, Motion sickness, Nausea and vomiting, Raised intracranial pressure, Vertigo.

Contraindications

Thiethylperazine is contraindicated in conditions like Coma.

Dosage

Thiethylperazine's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
4.25 mg4.25 mgEvery 8hIM,Slow IV
Paediatric Dosage (20kg)
0 – 0——Not recommended in this age group
Neonatal Dosage (3kg)
0 – 0——Not recommended in this age group

Drug Interactions

Unknown1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Thiethylperazine in overdosage may give rise to further complications which include Neuroleptic malignant syndrome .

Thiethylperazine is known to cause more or less tolerable side effects which are usually transient. These include Drowsiness, Dry mouth, Hypotension , SomnolenceX, Tachycardia.

Warnings / Precautions

Thiethylperazine should be used with caution in patients with pre-existing liver disease, seizure disorder, blood disorders, glaucoma, parkinsonism, asthma or if have any allergy. It should be used only if clearly needed during pregnancy or lactation. It may make person more sensitive to the sun, avoid prolonged sun exposure, wear protective clothing and use sunscreen when outdoors. It is recommended to avoid alcohol while taking this medication.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Inj
6.5 mg/ml

Storage Conditions

Thiethylperazine should be stored Inj. Suppositories. Tab.

Drug Classification

  1. 1.17.2 — Antiemetics & antinauseants

Manufacturers

Manufacturers of Thiethylperazine in Pakistan:

Novartis