Sitosterol
Sitosterol an antihyperlipidimic agent. Due to the structural similarity to cholesterol, Sitosterol competitively inhibits the absorsption of cholesterol. Sitosterolused to lower high blood cholesterol levels. Sitosterol lower the risk of heart attack by preventing the formation of plaque into the blood vessels..
Primary Characteristics
It is of Natural origin and belongs to Phytosterol.
It is classified in Prostatic Hyperplasia pharmacological group.
Molecular Weight: 414.7 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Sitosterol.
Pharmacokinetics
None recorded.
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Indications
Sitosterol is primarily indicated in conditions like Benign prostatic hyperplasia, Hyperlipidemia.
Contraindications
Sitosterol is contraindicated in conditions like Pregnancy, Breast feeding, Sitosterolemia.
Dosage
Sitosterol's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.29 mg/kg | 0.29 mg/kg | Every 8h | PO | - |
| Paediatric Dosage (20kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
| Neonatal Dosage (3kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Sitosterol is known to cause more or less tolerable side effects which are usually transient. These include Constipation , Diarrhea, Erectile dysfunction, Gas, Indigestion , Loss of libido, Nausea.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.12.6 — Lipid-regulating drugs /Anti-atheromas